Conclusion In the normal fetuses, CCD/ TCD is close to 1. When the ratio changed obviously, abnormal brain development may exist, especially for recessive abnormity of brain or heterotropic chromosome. 结论正常妊娠时CCD/ICD之比为1,当二者之比发生明显变化时,应高度怀疑异常的脑发育,尤其隐性的脑部异常或染色体异常。